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Program
Requirements
Course Offerings, Requirements,
Choosing a Thesis Advisor, Completing
Your Studies, Career Opportunites
Course Requirements. Ten credits
are required for the major. All students are required to take
two semesters of the 1 credit course, Topics in Microbiology
(MMI 810 & Micro 811). These 2 credits may be used for either
the major or the minor, with the approval of the thesis committee.
At least three courses must come from the following:
Course |
Title |
Info |
Micro 607 |
Advanced Microbial Genetics |
3cr. Lectures cover mutagenesis,
conjugation, transformation, transduction, plasmids,
cloning and transposable elements. P:Micro/Genetics/Biochem
612 or cons inst. |
Micro 612 |
Prokaryotic Molecular Biology |
3cr. Molecular basis of bacterial
physiology and genetics withemphasis on molecular mechanisms;
topics include nucleic acid-protein interactions, transcription,
translation, replication, recombination, regulation
of Gene expression. P:Micro 370 or equiv &; Biochem
501 or equiv, or cons inst. |
Micro 640 |
General Virology-Multiplication of
Viruses |
3cr. Bacterial and animal viruses,
their structure, multiplication, and genetics. P:Intro
courses in Micro, biochem & genetics. |
Micro 668 |
Microbiology at Atomic Resolution |
3 cr. Three-dimensional protein structures form the
basis for discussions of high resolution microbiology;
how particular problems are solved with given protein
architectures and chemistries and how themes of protein
structure are modified and recycled. P: Biochem (e.g.
Biochem 501), molecular biol (e.g. Micro 526 or 612)
required, one semester of physical chem preferred. |
MMI 720 |
Topics in Immunology |
3cr. Current questions in immunological research, designed to exploreselected topics in immunology, including genetic, cellular and molecular features of the immune system that are fundamental to the regulation of immune responses. P:MMI/AHABS/Micro 528 or equiv.
|
Micro 725 |
Microbial Physiology and Diversity |
3cr. Diversity of morphology, physiology
and ecology of bacteria and other microorganisms. Interrelationships
between microorganisms and their environment. P:Micro
550 or equiv, and Biochem 501 or 601 or con reg &
cons inst. |
Micro 726 |
Regulation of Gene Expression in
Prokaryotes |
3cr. An intensive examination of
a limited number of systems to illustrate the range
of molecular mechanism utilized to control gene expression
in bacteria. P:Micro/Genetics/Biochem 612 or cons inst.
|
MMI 740 |
Mechanisms of Microbial Pathogenesis |
3cr. Lecture-discussion. Host-pathogen
relationships in microbial diseases. Entry level course
for infectious diseases sequence (see Med Micro 760,
790). P:Cons inst, MMI 301 or equiv & a course in
immunology. |
MMI 750 |
Host-Parasite Relationships |
3cr Detailed study of the pathogenesis
of vertebrate viral disease, stressing viral invasion,
dissemination, mechanisms of disease production and
resistance, and transmission. P:Oncol/Micro 640 or Vet
Sci 513; and Micro, Vet Sci 528; or Cons Inst. |
MMI 760 |
Molecular Genetics of Microbial Pathogenesis |
3cr. The genetics and biochemistry
of host cell adherence, cellular invasion and immune
evasion by different human and animal microbial pathogens.
The mechanisms and regulation of adhesins, toxins and
antigenic variation. P:MMI 740 or equiv & cons inst.
|
MMI 773 |
Eukaryotic Microbial Pathogenesis |
3cr. An advanced course focusing
on the molecular, cellular, biochemical and pathogenicmechanisms
found in fungal and protozoan pathogens of humans. A
combination of lectures and student presentations will
be employed. P. Cons. Inst. MMI 740 and Path 750 recommended.
|
MMI 790 |
Immunology of Infectious Disease |
3 cr. Immunobiology and immunogenetics of resistance
to infectious disease agents of man and animals; immunoregulatory
mechanisms associated with evasion of host immunity.
P: MM&I 720 or equiv, MM&I 740 or equiv, &
cons inst. |
The remaining credits may come from other Bacteriology or MMI courses
approved by the Advising Committee or the Thesis Committee,
excluding Micro. 731/MMI 901, MMI 900, and Micro. or MMI 699
and 990, or any other research, directed study, seminar or
journal club course except as approved by the Steering Committee.
Course Offerings.
Graduate courses are offered in microbial physiology, microbial
and molecular genetics, microbial regulation and development,
microbial diversity, industrial microbiology and biotechnology,
immunology, microbial pathogenesis, virology, food microbiology,
biochemistry and microbiology of soils, and the microbiology
of plant pathogens. In addition, the departments periodically
offer special topics courses. Examples of past special topics
courses include: regulation of transcription, eucaryotic cell
cycle, bacterial DNA replication, transcription termination
and anti-termination, posttranscriptional regulation of gene
expression, secondary metabolism and drug production, and
practical aspects of HPLC, cell biology, and microscopy.
Requirements for
the Minor. The Graduate School requires that each student
fulfill a Ph.D. minor program. The minor can be completed
by either taking 10 graduate credits from one discipline outside
of the microbiology major, or by taking 10 credit hours distributed
among courses from any department related to the individual
training emphasis area. This can include Bacteriology or MMI courses
not used for the major.
Grade Requirement. A student must
maintain a B average in all courses to meet degree requirements.
Grades of S areconsidered to be satisfactory; an incompletegrade
must be removed during the following semester of residence
or it will be converted to F. A student taking minor option
A must satisfy the grade requirements of the minor department.
Department Seminar and/or Journal Club.
Throughout their graduate study, students must register for
and attend the weekly seminar, Micro. 731/MMI 901. Students are required to make at least one
seminar presentation per academic year after achieving dissertator
status. At least two of these presentations must be in Micro.
731/MMI 901.
Graduate Study Prior
to Choosing a Thesis Adviser. During the week prior
to the start of classes in the fall semester, each student
must attend orientation activities and meet with the Advising
Committee. The Committee reviews background course requirements,
considers training emphasis area (if known) and devises a
course of study for the first year. The Advising Committee
also monitors rotations and is available for advice until
a thesis advisor is identified. If a student is funded by
certain training program grants, the student may also be assigned
a specific adviser who represents that program until a thesis
adviser is identified.
During the initial 6 months of graduate study, students complete
at least 3 research rotations with 3 different program faculty
or trainers. The length and timing of rotations will be decided
by the individual student in consultation with the faculty
with whom they are rotating, although 3-4 rotations of 1-2
months each is appropriate. Students may select a thesis adviser
as early as Dec. 15, but no later than Feb. 21 of the first
year. Deviation from the minimal number of rotations or dates
for selection of a thesis adviser requires approval of the
Advising Committee. A student who fails to select a thesis
advisor by July 1 of the first year may be dismissed from
the Program.
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Graduate Study after Choosing a Thesis
Adviser. Formulation of the Thesis
Committee. A committee consisting of five faculty members
guides the student's progress towards the degree. At least
one member must be outside the thesis adviser's department.
Students form their committees at the end of their second
semester and submit the names of the committee members to
the Steering Committee for approval. At least 2 members of
a student's thesis committee besides the thesis advisor must
be members of the core faculty of the Bacteriology or Medical
Microbiology and Immunology departments. Initial
Meeting. The student may write a brief description
of research planned for the next year (1-2) pages is sufficient)
by June 15 of the first year, distribute the write-up to the
committee and meet with the committee prior to August 15.
At the meeting, the student's coursework for completion of
degree requirements will be approved. Annual
Meetings with Thesis Committee. Students are required
to prepare a brief progress report and hold an annual meeting
with the committee. The student is responsible for obtaining
committee member signatures and turningthese in to the Program
Office.
Completion of Graduate
Studies. Teaching Requirement.
As part of their training, students are required to perform
two semesters of teaching. Waivers of one semester may be
granted for special circumstances by the Steering Committee
in consultation with the appropriate departmental administrator.
Preliminary Examination. Before
the first day of spring semester classes in the third year
in the Microbiology Ph.D. program, students will complete
the requirements of the qualifying exam, which is centered
around a research proposal. The exam consists of two parts,
the written proposal and an oral defense by the student before
the members of the Thesis Committee.
The Written Proposal (Part A).
The student writes and submits the research proposal to the
Thesis Committee. The subject matter of the proposal will
coincide with the student's anticipated thesis research. The
proposal will be prepared in the format of a National Institutes
of Health research proposal, but approximately 15 double-spaced
pages long. (A guideline for the written proposal will be
provided.) The student should consult with others, including
the thesis adviser and committee members, before and during
the writing process. at least 6 weeks prior to the anticipated
oral defense, the student will submit the proposal to the
members of the committee. The committee will have two weeks
to evaluate the proposal. During the third week, the student
should meet with each member of the committee to learn his/her
appraisal. Based on the these comments, the student will revise
the proposal and resubmit it at least one week prior to the
oral defense. If a committee member has reservations about
the original or the revised proposal that are serious enough
to make voting to "pass" unlikely, that member should
notify the student and the thesis adviser of his/her concerns
immediately. In such cases, the thesis adviser, after consultation
with the other committee members may delay the defense to
allow time for corrective actions.
The Oral Defense (Part B). The
student will give a brief (20-30 min.) oral presentation describing
the research proposal and then respond to questions raised
by the members of the Thesis Committee. The questions will
center around the research proposal, but may include any question
relevant to it or to the expected proficiencies in microbiology
enumerated by the Steering Committee. Following the examination,
the Thesis Committee will decide whether the student (i) passes
the exam unconditionally and proceeds to candidacy, (ii) passes
the exam conditionally and is instructed to complete additional
work to satisfy a perceived deficiency, or (iii) fails the
exam.
Candidacy. After the student has
passed the Preliminary Examination and all other degree requirements
have been met, the Graduate School warrant certifying candidacy
for the Ph.D. will be signed by the Thesis Committee and returned
to the Graduate School.
Procedure for Appeal. A student
who fails the Preliminary Examination may be offered a second
opportunity to pass the qualifying examination or may be dismissed
from the program. Appeals of a decision by the Thesis Committee
must be made to the Steering Committee within two weeks or
they will be final. The Steering Committee will make the final
decision on an appeal. A student who has not satisfied the
qualifying examination requirement within 36 months of entering
the Ph.D. program will be dropped from the program, except
by appeal in writing to the Steering Committee, which will
make the final decision.
Thesis and Final Defense. Prior
to graduation, every student must submit a thesis based on
original and significant observations. Six months prior to
the expected defense date, the student will meet with the
Thesis Committee and obtain approval of the thesis prospectus.
Students are required to present a seminar on his/her dissertation
research, which is followed directly by the final examination.
The final examination will be an oral defense of the thesis
to the Thesis Committee. One month prior to the scheduled
oral defense, the student must obtain the Ph.D. warrant from
the Graduate School. For the students to pass the final exam,
four of the five committee members must sign to affirm passage.
Career Opportunities
for Program Graduates. UW-Madison Microbiology graduates
compete successfully for positions in the nation's most prestigious
academic institutions, industrial and clinical laboratories,
and government agencies. The Program maintains a comprehensive
Career
Resource Guide and Job
Bulletin with updated information on career and employment
opportunities. If you need assistance with career and job
exploration, as well as help with developing your CV, please
contact Katy France
in 1328 Microbial Sciences or at 608-262-2975.
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